Kidneys remove wastes from the bloodstream. When the kidneys fail, the build-up of wastes in your blood can cause severe itching. ...

It is a symptom relatively easy to be detected, that is because the kidneys can not promptly remove the excess water in the body. In early stage, only foot and ankle and eyelids are swelling which always disappear after having a rest. Further development of persistent or generalized edema, generally has entered the period of typical uremia. ...